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991.
An automatic measurement system for evaluating powder flowability based on the vibrating capillary method has been studied experimentally. The vibration amplitude was controlled by a computer, and the vibration acceleration and the mass of particles discharged from the capillary were obtained by digital processing. The measurement time was 2 min and the amount of the powder required for each measurement was less than a few grams. To characterize the dynamic powder flowability, evaluation factors were developed. A series of experiments was conducted using powders with mass median diameters from 5.2 to 58.2 μm, showing that this measurement system can fully evaluate the powder flowability.  相似文献   
992.
The die casting process and its alloys have been developed in recent years for automobile body parts such as B-pillars. However, it is known that die casting alloys with high ductility and fracture elongation often show a higher susceptibility to cracking during solidification than conventional Al–Si alloys. Thus, it is important to estimate and control the susceptibility to cracking during solidification before trial casting or mass-production. In this study, as a representative non-heat treatment type alloy, Al–4.5wt%Mg (JIS AC7A, AA 514) aluminum alloy was used. The effect of the addition of silicon and grain refiner on the reduction of the susceptibility to cracking was examined. In order to evaluate the susceptibility to cracking, both the “I-beam casting cracking test” and the “TIG spot welding cracking test” were carried out. As a result, the addition of Ti + B worked as a grain refiner on both testing methods. The susceptibility to cracking was significantly reduced by the addition of Ti + B in both the I-beam casting and the weld crater. It was found that the finer grain size led to lower susceptibility to cracking. Furthermore, the susceptibility to cracking of the die casting product decreased with the addition of Ti + B.  相似文献   
993.
The machining accuracy prediction has been widely studied in many manufacturing processes to achieve efficient control for production process. In this paper, a dynamic analysis model is proposed to develop the prediction model of machining accuracy. The dynamic analysis model has the advantage of high predictable power of the GM(1,1) model while at the same time utilizing the prediction power of the Markov chain model from stochastic process theory. Furthermore, Taylor approximation method is employed to enhance the prediction accuracy. The effectiveness of the proposed model is validated with a real case.  相似文献   
994.
    
Glycidol fatty acid esters that are present in foods are degraded in vivo to the animal carcinogen glycidol, which binds to the N-terminal valine of hemoglobin (Hb) to form N-(2,3-dihydroxypropyl)valine (diHOPrVal) adducts. The existence of other chemicals that are converted to glycidol is unknown. To determine the effect of different exposure conditions on the formation of diHOPrVal adducts, several glycidol-related chemicals (3-monochloropropane-1,2-diol; 3-MCPD, epichlorohydrin, glyceraldehyde, acrylic acid, and 1,2-propanediol) were evaluated using in vitro and in vivo (single/repeated dose) methods. In vitro, the reaction of 3-MCPD or epichlorohydrin with human Hb produced 17% and 0.7% of diHOPrVal, as compared to equimolar glycidol, respectively. Following a single administration of glycidol-related compounds to ICR mice, diHOPrVal formation was observed only in the epichlorohydrin-treated group after day 5 of exposure. After 14 days of repeated dosing, the amounts of diHOPrVal produced by epichlorohydrin and 3-MCPD in vivo were <1% of diHOPrVal produced by an equal molar concentration of glycidol. Furthermore, glyceraldehyde group produced 0.2% of diHOPrVal at the same molar concentration of glycidol equivalents, in which diHOPrVal formation could not be confirmed by the in vitro assay. The results indicate the usefulness of diHOPrVal as an exposure marker for glycidol; however, the contribution of its formation in vivo by exposure to various chemicals will be necessary to validate and interpret the results.  相似文献   
995.
996.
    
In this study, flash joining experiments were conducted using an AC field on 3 mol% Y2O3-stabilized tetragonal ZrO2 polycrystal (Y-TZP) bodies. Furthermore, the necessary conditions to obtain an almost complete self-joining of Y-TZP bodies were clarified. The specimens were successfully joined by applying an AC field at 60 mA mm−2 for 80 s at a furnace temperature of 1000°C, thus resulting in a successfully joined specimen with 92% of the flexural strength of the as-sintered Y-TZP body. Almost complete self-joining of Y-TZP was achieved at current densities above 30 mA mm−2, and input energy densities of >24 J mm−3. Both the input energy density and electric current were critical factors for producing the reliable joining of ceramics.  相似文献   
997.
    
Balloon-type actuators have attracted scientific attention because they allow easy control of the output intensity and a high degree-of-freedom regarding shape and movement. However, they require bulky external pumps and electric power suppliers. This makes miniaturization and wearable device fabrication difficult. Herein, a balloon soft actuator that does not require a pneumatic pump or electric power supplier, and that uses a finger-operated pump based on a fluidic circuit and catalytic reaction, is proposed. This device can be driven without electric power multiple times by applying a vent valve system to exhaust the generated gas. Further, it is applied to two different types of applications—soft robots and wearable devices—by optimizing their structure and material. In conclusion, the proposed device is expected to lead to the development of a broad range of soft actuators for stand-alone robots and wearable devices in the future.  相似文献   
998.
    
Natural membrane vesicles, including extracellular vesicles and enveloped viruses, participate in various events in vivo. To study and manipulate these events, biomembrane-coated nanoparticles inspired by natural membrane vesicles are developed. Herein, an efficient method is presented to prepare organic–inorganic hybrid materials in high yields that can accommodate various lipid compositions and particle sizes. To demonstrate this method, silica nanoparticles are passed through concentrated lipid layers prepared using density gradient centrifugation, followed by purification, to obtain lipid membrane-coated nanoparticles. Various lipids, including neutral, anionic, and cationic lipids, are used to prepare concentrated lipid layers. Single-particle analysis by imaging flow cytometry determines that silica nanoparticles are uniformly coated with a single lipid bilayer. Moreover, cellular uptake of silica nanoparticles is enhanced when covered with a lipid membrane containing cationic lipids. Finally, cell-free protein expression is applied to embed a membrane protein, namely the Spike protein of severe acute respiratory syndrome coronavirus 2, into the coating of the nanoparticles, with the correct orientation. Therefore, this method can be used to develop organic–inorganic hybrid nanomaterials with an inorganic core and a virus-like coating, serving as carriers for targeted delivery of cargos such as proteins, DNA, and drugs.  相似文献   
999.
    
The objective of this study is to realize efficient learning for the high generalization ability of evolutionary artificial neural network (EANN). In order to achieve this objective, the evolutionary process of behavior acquisition is analyzed, and then an efficient evaluation function is led by the analysis. An artificial flying creature (AFC) is controlled to fly towards a given target point by EANN. The three-dimensional motion of the AFC is calculated by the physical engine PhysX and a numerical expression of the simple drag force. To evolve ANNs and to have the AFC flight suitably for given target points, particle swarm optimization optimizes parameters of ANNs. The results of evolutionary simulation show that generalization ability of ANNs does not always increase as evolution progresses, and it depends on given tasks of the AFC. It is also shown that diversity of input signals about target points, which the AFC goes through in flight, has positive correlation with generalization ability.  相似文献   
1000.
    
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